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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
6.97
Human Site:
S557
Identified Species:
11.79
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S557
T
G
N
S
V
A
S
S
P
C
P
N
E
L
D
Chimpanzee
Pan troglodytes
XP_509445
540
59236
P391
G
N
S
V
A
S
S
P
C
P
N
E
L
D
L
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S557
T
G
N
S
V
A
S
S
P
C
P
N
E
L
D
Dog
Lupus familis
XP_534658
709
78944
C559
N
S
V
V
S
S
P
C
P
H
E
L
D
L
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S559
L
T
G
N
S
V
A
S
S
P
C
P
N
E
F
Rat
Rattus norvegicus
NP_001099399
476
51796
P327
A
N
S
D
S
D
V
P
M
D
T
P
L
T
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
S566
N
S
V
T
S
S
P
S
R
N
E
Q
P
A
T
Chicken
Gallus gallus
Q5F3D1
613
68449
G464
P
V
D
T
P
L
T
G
N
S
V
T
S
S
P
Frog
Xenopus laevis
Q6DD45
743
82926
F594
P
C
V
I
T
K
L
F
V
A
E
P
E
E
G
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
L541
S
P
S
V
V
T
S
L
K
F
D
T
E
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
P404
L
P
P
S
V
P
P
P
Q
P
P
P
P
E
E
Honey Bee
Apis mellifera
XP_001122586
556
62911
S407
P
P
L
P
Q
T
I
S
E
D
S
D
Y
H
S
Nematode Worm
Caenorhab. elegans
P34656
453
51815
V304
A
N
E
D
D
D
D
V
I
V
I
T
S
D
E
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
E477
T
K
L
L
A
A
L
E
K
G
A
D
S
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
100
13.3
N.A.
6.6
0
N.A.
6.6
0
6.6
26.6
N.A.
20
6.6
0
13.3
P-Site Similarity:
100
20
100
26.6
N.A.
20
6.6
N.A.
20
20
6.6
40
N.A.
26.6
13.3
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
15
22
8
0
0
8
8
0
0
8
0
% A
% Cys:
0
8
0
0
0
0
0
8
8
15
8
0
0
0
0
% C
% Asp:
0
0
8
15
8
15
8
0
0
15
8
15
8
22
22
% D
% Glu:
0
0
8
0
0
0
0
8
8
0
22
8
29
22
15
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
8
% F
% Gly:
8
15
8
0
0
0
0
8
0
8
0
0
0
0
15
% G
% His:
0
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% H
% Ile:
0
0
0
8
0
0
8
0
8
0
8
0
0
0
8
% I
% Lys:
0
8
0
0
0
8
0
0
15
0
0
0
0
0
0
% K
% Leu:
15
0
15
8
0
8
15
8
0
0
0
8
15
22
8
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
15
22
15
8
0
0
0
0
8
8
8
15
8
0
0
% N
% Pro:
22
22
8
8
8
8
22
22
22
22
22
29
15
0
15
% P
% Gln:
0
0
0
0
8
0
0
0
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% R
% Ser:
8
15
22
22
29
22
29
36
8
8
8
0
22
15
8
% S
% Thr:
22
8
0
15
8
15
8
0
0
0
8
22
0
8
8
% T
% Val:
0
8
22
22
29
8
8
8
8
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _